Jisc has taken just over 11,000 sq ft in Churchgate House in Manchester.
Jisc champion the use of digital technologies in UK education and research.
The charity has signed a 10-year lease for the office space on the sixth floor.
Churchgate House is currently undergoing a refurbishment programme, the office property will offer an open-plan floor-plate, an upgraded reception with a new coffee hub and business lounge. The landlord, Helical Bar will have the works completed by April 2015.
OBI Property and CBRE acted for Helical Bar.
Jisc was represented by LSH.